Amino acids in the regulation of aging and aging-related diseases
Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target
Tryptophan is an essential amino acid that our bodies cannot produce on their own, making it crucial to obtain through our diet or supplements. While it is primarily known for its role in serotonin production and mood regulation, recent research has uncovered its potential benefits for our skin. Tryptophan is a precursor to serotonin, a neurotransmitter that regulates various physiological processes, including skin barrier function. Serotonin helps maintain the integrity of the skin barrier, which is essential for protecting against environmental stressors and maintaining optimal hydration levels. Tryptophan also exhibits antioxidant and anti-inflammatory properties, which are crucial for maintaining skin health. It helps neutralize free radicals, reducing oxidative stress and preventing damage to skin cells. Additionally, tryptophan can modulate inflammatory responses, mitigating the harmful effects of inflammation. Furthermore, tryptophan is involved in collagen synthesis, the protein responsible for maintaining skin elasticity and firmness. [12]
Friedman, M., Analysis, Nutrition, and Health Benefits of Tryptophan. Int J Tryptophan Res, 2018. 11: p. 1178646918802282.